DL-homatropine hydrobromide

DL-homatropine hydrobromide structure formula

Structural formula

Physical competition number 0151
Molecular formula C16H22BrNO3
Molecular weight 356.3
label

homatropine hydrobromide,

Alpha-Hydroxyphenylacetate Hydrobromide,

8-Methyl-8-azabicyclo[3.2.1]octan-3-ol,

Phenyl glycoltropine hydrobromide,

Tropine mandelate hydrobromide,

anticholinergics,

Mydriatic medicine

Numbering system

CAS number:51-56-9

MDL number:MFCD00012676

EINECS number:200-105-3

RTECS number:YM5602000

BRN number:None

PubChem ID:None

Physical property data

1. Properties: white orthorhombic bipyramidal prism crystal or powder. Odorless. Very bitter taste.

2. Density (g/mL, 25/4℃): Undetermined

3. Relative vapor density (g/mL, air=1): Undetermined

4. Melting point (ºC): 212 (partially decomposed)

5. Boiling point (ºC, normal pressure): Undetermined

6. Boiling point (ºC, 5.2kPa ): Not determined

7. Refractive index: Not determined

8. Flash point (ºC): Not determined

9. Specific rotation (º) : Undetermined

10. Autoignition point or ignition temperature (ºC): Undetermined

11. Vapor pressure (kPa, 25ºC): Undetermined

12. Saturated vapor pressure (kPa, 60ºC): Undetermined

13. Heat of combustion (KJ/mol): Undetermined

14. Critical temperature (ºC): Undetermined

15. Critical pressure (KPa): Undetermined

16. Log value of oil-water (octanol/water) partition coefficient: Undetermined

17. Explosion Upper limit (%, V/V): Undetermined

18. Lower explosion limit (%, V/V): Undetermined

19. Solubility: 1g product dissolves in 6ml water , 40ml ethanol, 420ml chloroform, insoluble in ether. Its solubility decreases with increasing temperature.

Toxicological data

1. Acute toxicity:; rat abdominal LD50: 154mg/kg; mouse intravenous LD50: 107mg/kg

Ecological data

None

Molecular structure data

1. Molar refractive index: 76.15

2. Molar volume (cm3/mol): 226.1

3. Isotonic specific volume (90.2K ): 606.0

4. Surface tension (dyne/cm): 51.5

5. Polarizability (10-24cm3): 30.19

Compute chemical data

None

Properties and stability

None

Storage method

Should be sealed, dry and protected from light.

Synthesis method

None

Purpose

This product is a synthetic anticholinergic drug that blocks acetylcholine and paralyzes the pupillary sphincter and cycloplegic muscles, causing mydriasis and accommodation paralysis. It is faster and weaker than atropine and is suitable for eye examinations. and optometry.

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