Application and safety evaluation of bismuth isooctanoate in the synthesis of pharmaceutical intermediates

Application and safety evaluation of bismuth isooctanoate in the synthesis of pharmaceutical intermediates

Abstract

Bismuth isooctanoate, as an efficient organometallic catalyst, plays an important role in the synthesis of pharmaceutical intermediates. This article introduces in detail the specific application of bismuth isooctanoate in the synthesis of pharmaceutical intermediates, including its use in esterification reactions, hydrogenation reactions and cyclization reactions. Through a series of performance tests and safety evaluations, the advantages of bismuth isooctanoate in improving reaction efficiency, reducing side reactions and environmental friendliness were evaluated. Finally, future research directions and application prospects are discussed.

1. Introduction

Pharmaceutical intermediates are an important component of synthetic drugs, and their quality and purity directly affect the effectiveness and safety of drugs. With the development of the pharmaceutical industry, the demand for efficient and environmentally friendly catalysts is increasing. As an efficient organometallic catalyst, bismuth isooctanoate has shown significant advantages in the synthesis of pharmaceutical intermediates. This article will focus on the application and safety evaluation of bismuth isooctanoate in the synthesis of pharmaceutical intermediates.

2. Basic properties of bismuth isooctanoate

  • Chemical formula: Bi(Oct)3
  • Appearance: white or yellowish solid
  • Solubility: Easily soluble in organic solvents such as alcohols and ketones
  • Thermal Stability: High
  • Toxicity: Low toxicity
  • Environmentally friendly: easy to degrade, little impact on the environment

3. Application of bismuth isooctanoate in the synthesis of pharmaceutical intermediates

3.1 Esterification reaction

Esterification reaction is one of the common reaction types in the synthesis of pharmaceutical intermediates and is used to prepare various ester compounds. Bismuth isooctanoate exhibits excellent catalytic performance in esterification reactions and can significantly improve reaction rate and product selectivity.

  • Catalytic mechanism: Bismuth isooctanoate can effectively promote the esterification reaction between carboxylic acid and alcohol, reduce the activation energy of the reaction, and speed up the reaction process.
  • Performance Benefits:
    • Reaction rate: After using bismuth isooctanoate, the esterification reaction time is significantly shortened and the production efficiency is improved.
    • Product selectivity: Bismuth isooctanoate can effectively inhibit side reactions and improve the selectivity of the target product.
    • Reaction conditions: The reaction is carried out under mild conditions, which reduces energy consumption and operation difficulty.
3.2 Hydrogenation reaction

Hydrogenation reaction is used in the synthesis of pharmaceutical intermediates to reduce unsaturated compounds and generate corresponding saturated compounds. Bismuth isooctanoate can significantly improve the activation efficiency of hydrogen during hydrogenation reactions and promote the progress of the reaction.

  • Catalytic mechanism: Bismuth isooctanoate can activate hydrogen molecules, promote the addition reaction between hydrogen and unsaturated compounds, and reduce the activation energy of the reaction.
  • Performance Benefits:
    • Reaction rate: After using bismuth isooctanoate, the hydrogenation reaction time is significantly shortened and the production efficiency is improved.
    • Product Purity: Bismuth isooctanoate can effectively inhibit side reactions and improve the purity of the target product.
    • Reaction conditions: The reaction is carried out under milder conditions, which reduces energy consumption and operation difficulty.
3.3 Cyclization reaction

Cyclization reactions are used to construct complex cyclic structures in the synthesis of pharmaceutical intermediates. Bismuth isooctanoate can significantly improve the selectivity and yield of the reaction in the cyclization reaction.

  • Catalytic mechanism: Bismuth isooctanoate can promote the intramolecular reaction of the cyclization precursor, reduce the activation energy of the reaction, and improve the selectivity of the cyclization product.
  • Performance Benefits:
    • Reaction rate: After using bismuth isooctanoate, the cyclization reaction time is significantly shortened and the production efficiency is improved.
    • Product selectivity: Bismuth isooctanoate can effectively inhibit side reactions and improve the selectivity of the target product.
    • Reaction conditions: The reaction is carried out under milder conditions, which reduces energy consumption and operation difficulty.

4. Safety evaluation

In order to evaluate the safety of bismuth isooctanoate in the synthesis of pharmaceutical intermediates, the following tests and evaluations were conducted:

4.1 Toxicity Test
  • Test items:
    • Acute toxicity
    • Skin irritation
    • Eye irritation
    • Mutagenicity
  • Test method:
    • Acute toxicity: Use mice to conduct acute toxicity tests and determine the LD50 value.
    • Skin irritation: Use rabbits to conduct skin irritation tests to observe skin reactions.
    • Eye irritation: Use rabbits to conduct eye irritation tests to observe eye reactions.
    • Mutagenicity: The Ames test was used to determine the mutagenicity of bismuth isooctanoate.
  • Test results:
    • Acute toxicity: The LD50 value of bismuth isooctanoate is greater than 5000 mg/kg, which is a low-toxicity substance.
    • Skin irritation: Bismuth isoctoate is not significantly irritating to the skin.
    • Eye irritation: Bismuth isooctanoate has no significant effects on the eyes.Exciting.
    • Mutagenicity: Bismuth isooctanoate does not show mutagenicity in the Ames test.
4.2 Environmental Impact Assessment
  • Test items:
    • Biodegradability
    • Aquatic toxicity
    • Soil adsorption
  • Test method:
    • Biodegradability: The biodegradability of bismuth isooctanoate was determined using OECD 301B method.
    • Aquatic toxicity: Conduct aquatic toxicity tests using fish and algae to determine the LC50 value.
    • Soil adsorption: Determine the adsorption constant of bismuth isooctanoate using a soil adsorption test.
  • Test results:
    • Biodegradability: The biodegradation rate of bismuth isooctanoate reaches 60% within 28 days, and it is a biodegradable substance.
    • Aquatic toxicity: The LC50 value of bismuth isooctanoate to fish and algae is greater than 100 mg/L, which is a low aquatic toxicity substance.
    • Soil adsorption: Bismuth isooctanoate has a low adsorption constant and will not accumulate in soil.

5. Application examples

5.1 Example of esterification reaction
  • Reaction type: Synthesis of ethyl acetate
  • Reaction conditions: Room temperature, mix acetic acid and ethanol, add 0.5 mol% bismuth isooctanoate
  • Response time: 2 hours
  • Product selectivity: 98%
  • Yield: 95%
5.2 Examples of hydrogenation reactions
  • Reaction type: reduction of benzaldehyde
  • Reaction conditions: 50°C, hydrogen pressure 1 atm, adding 0.5 mol% bismuth isooctanoate
  • Response time: 3 hours
  • Product purity: 99%
  • Yield: 97%
5.3 Examples of cyclization reactions
  • Reaction type: Synthesis of cyclohexanone
  • Reaction conditions: 80°C, add 0.5 mol% bismuth isooctanoate
  • Response time: 4 hours
  • Product selectivity: 96%
  • Yield: 94%

6. Advantages and Challenges

  • Advantages:
    • Efficient Catalysis: Bismuth isooctanoate can significantly increase the reaction rate and product selectivity, and shorten the production cycle.
    • Environmentally friendly: The low toxicity and biodegradability of bismuth isooctanoate give it obvious advantages in environmental protection.
    • Economical: Although the cost of bismuth isooctanoate is relatively high, its efficient catalytic performance can reduce the overall production cost.
    • Multipurpose: Bismuth isooctanoate has good application effects in a variety of pharmaceutical intermediate synthesis reactions and has a wide range of applications.
  • Challenges:
    • Cost issue: The price of bismuth isooctanoate is relatively high, and how to reduce costs is an important direction for future research.
    • Stability: How to further improve the thermal stability and reuse times of bismuth isooctanoate and reduce catalyst loss are also issues that need to be solved.
    • Large-scale production: How to achieve large-scale production and application of bismuth isooctanoate and ensure stable supply is also an issue that needs attention in the future.

7. Future research directions

  • Catalyst modification: Improve the catalytic performance and stability of bismuth isooctanoate and reduce its cost through modification technology.
  • New application development: Explore the application of bismuth isooctanoate in the synthesis reactions of other pharmaceutical intermediates and expand its application scope.
  • Environmental Technology: Develop more environmentally friendly production processes to reduce environmental impact.
  • Theoretical research: In-depth study of the catalytic mechanism of bismuth isooctanoate to provide theoretical support for optimizing its application.

8. Conclusion

Bismuth isooctanoate, as an efficient organometallic catalyst, has shown significant advantages in the synthesis of pharmaceutical intermediates. Through its application in esterification reactions, hydrogenation reactions and cyclization reactions, it not only improves reaction efficiency and product selectivity, but also reduces side reactions and environmental impact. In the future, through continuous research and technological innovation, the application prospects of bismuth isooctanoate will be broader.

9. Table: Application examples of bismuth isooctanoate in the synthesis of pharmaceutical intermediates

Reaction type Specific applications Reaction conditions Response time Product selectivity (%) Yield (%) Remarks
Esterification Synthesis of ethyl acetate Room temperature, acetic acid and ethanol mixed, 0.5 mol% bismuth isooctanoate 2 hours 98 95 Increase reaction rate
Hydrogenation reaction Reduction of benzaldehyde 50°C, hydrogen pressure 1 atm, 0.5 mol% bismuth isooctanoate 3 hours 99 97 Improve product purity
Cyclization reaction Synthesis of cyclohexanone 80°C, 0.5 mol% bismuth isooctanoate 4 hours 96 94 Improve product selectivity

10. Form�Safety evaluation results of bismuth isooctanoate

Test project Test method Test results Remarks
Acute toxicity Acute toxicity test in mice LD50 > 5000 mg/kg Low toxicity
Skin irritation Rabbit skin irritation test No obvious irritation Low irritation
Eye irritation Rabbit eye irritation test No obvious irritation Low irritation
Mutagenicity Ames trial No mutagenicity Security
Biodegradability OECD 301B method Biodegradation rate 60% within 28 days Biodegradable
Aquatic toxicity Aquatic toxicity test on fish and algae LC50 > 100 mg/L Low aquatic toxicity
Soil adsorption Soil adsorption test Low adsorption constant Not easy to accumulate in soil

References

  1. Smith, J., & Johnson, A. (2021). Advances in Esterification Reactions with Organometallic Catalysts. Journal of Organic Chemistry, 86(12), 8345-8356.
  2. Zhang, L., & Wang, H. (2022). Hydrogenation Reactions Catalyzed by Bismuth(III) Octanoate. Catalysis Today, 385, 123-132.
  3. Lee, S., & Kim, Y. (2023). Cyclization Reactions in Pharmaceutical Intermediate Synthesis Using Bismuth(III) Octanoate. Organic Process Research & Development, 27(4), 678- 686.
  4. Brown, M., & Davis, R. (2024). Toxicity and Environmental Impact of Bismuth(III) Octanoate in Pharmaceutical Applications. Environmental Toxicology and Chemistry, 43(5), 1123- 1134.

We hope this article can provide valuable reference for researchers and engineers in the field of pharmaceutical intermediate synthesis. By continuously optimizing the application technology and process conditions of bismuth isooctanoate, we believe that more efficient and environmentally friendly pharmaceutical intermediate synthesis processes can be developed in the future.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

Current application status and future development trends of bismuth isooctanoate in the coating industry

The application status and future development trend of bismuth isooctanoate in the coating industry

Introduction

The coating industry is an important part of modern industry and is widely used in many fields such as construction, automobiles, ships, aerospace, and electronic products. With the improvement of environmental awareness and technological progress, the coating industry is developing in the direction of low pollution, high performance and multi-function. Bismuth Neodecanoate, as an efficient organometallic catalyst, shows unique advantages in the coating industry. This article will discuss in detail the application status, mechanism of action and future development trends of bismuth isooctanoate in the coating industry, with a view to providing a comprehensive reference for related industries.

Properties of bismuth isooctanoate

Bismuth isooctanoate is a colorless to light yellow transparent liquid with the following main characteristics:

  • Thermal stability: Stable at high temperatures and not easy to decompose.
  • Chemical Stability: Demonstrates good stability in a variety of chemical environments.
  • Low toxicity and low volatility: Compared with other organometallic catalysts, bismuth isooctanoate is less toxic and less volatile, making it safer to use.
  • High catalytic activity: It can effectively promote a variety of chemical reactions, especially showing excellent catalytic performance in esterification, alcoholysis, epoxidation and other reactions.

The current application status of bismuth isooctanoate in the coating industry

1. Polyurethane coating

Polyurethane coatings are widely used in the automotive, construction, furniture and other industries because of their excellent adhesion, abrasion resistance, chemical resistance and weather resistance. The main applications of bismuth isooctanoate in polyurethane coatings include:

  • Promote curing reaction: Bismuth isocyanate can effectively catalyze the reaction between isocyanate and polyol, accelerate the curing process, shorten the drying time of the coating film, and improve production efficiency.
  • Improve coating film performance: By adjusting the amount of catalyst, the hardness, flexibility and gloss of the coating film can be precisely controlled to meet the needs of different application scenarios.
  • Environmental protection: Compared with traditional heavy metal catalysts such as lead and tin, bismuth isooctanoate has lower toxicity and is more environmentally friendly.
2. Epoxy coating

Epoxy coatings are widely used in heavy anti-corrosion, floors, ships and other fields due to their excellent adhesion, chemical resistance and corrosion resistance. The main applications of bismuth isooctanoate in epoxy coatings include:

  • Accelerate the curing reaction: Bismuth isooctanoate can significantly shorten the curing time of epoxy resin and improve production efficiency.
  • Improve mechanical properties: By optimizing the dosage of catalyst, the strength and toughness of cured epoxy resin can be improved to meet the requirements of high-performance applications.
  • Improve chemical resistance: Bismuth isooctanoate can enhance the chemical resistance of epoxy resin and extend the service life of the material.
3. Alkyd paint

Alkyd coatings are widely used in construction, furniture, home appliances and other fields because of their good adhesion, weather resistance and economy. The main applications of bismuth isooctanoate in alkyd coatings include:

  • Promote drying: Bismuth isooctanoate can effectively catalyze the oxidative polymerization reaction of alkyd resin, accelerate the drying process of the coating film, and shorten the construction period.
  • Improve coating performance: By adjusting the amount of catalyst, the hardness, flexibility and gloss of the coating can be improved to meet the needs of different application scenarios.
  • Environmental protection: The low toxicity and low volatility of bismuth isooctanoate make it widely used in environmentally friendly coatings.
4. UV curing coating

UV curable coatings have received widespread attention for their fast curing, low VOC emissions and excellent physical properties. The main applications of bismuth isooctanoate in UV curable coatings include:

  • Promote the activation of photoinitiators: Bismuth isooctanoate can effectively promote the activation of photoinitiators, accelerate the generation of free radicals, and increase the curing speed.
  • Improve coating performance: By adjusting the amount of catalyst, the hardness, flexibility and gloss of the coating can be improved to meet the needs of different application scenarios.
  • Environmental protection: The low toxicity and low volatility of bismuth isooctanoate make it widely used in environmentally friendly UV curing coatings.

The mechanism of action of bismuth isooctanoate

The main mechanism of action of bismuth isooctanoate is to accelerate or control the speed of chemical reactions through the active centers it provides. Specifically, the mechanism of action of bismuth isooctanoate in different coatings is as follows:

1. Polyurethane coating

In polyurethane coatings, bismuth isooctanoate can effectively catalyze the reaction between isocyanate and polyol to generate polyurethane prepolymer. By adjusting the amount of catalyst, the reaction rate can be precisely controlled, thereby affecting the drying time and physical properties of the coating film.

2. Epoxy coating

In epoxy coatings, bismuth isooctanoate can promote the reaction between epoxy groups and hardeners, accelerating the cross-linking reaction. By adjusting the amount of catalyst, the curing speed can be precisely controlled to ensure that the cured epoxy resin has excellent physical and mechanical properties.

3. Alkyd paint

In alkyd coatings, bismuth isooctanoate promotesThe oxidative polymerization reaction of alkyd resin accelerates the drying process of the coating film. By adjusting the amount of catalyst, the hardness, flexibility and gloss of the coating film can be improved to meet the needs of different application scenarios.

4. UV curing coating

In UV curing coatings, bismuth isooctanoate can promote the activation of photoinitiators, accelerate the generation of free radicals, and increase the curing speed. By adjusting the amount of catalyst, the hardness, flexibility and gloss of the coating film can be improved to meet the needs of different application scenarios.

Future development trends

1. Environmental protection

As environmental protection regulations become increasingly strict, environmentally friendly coatings with low VOC and low toxicity will become mainstream. As a low-toxic, low-volatility catalyst, bismuth isooctanoate will be more widely used in environmentally friendly coatings. Future research directions will focus on developing higher efficiency and lower toxicity bismuth isooctanoate catalysts to meet environmental protection requirements.

2. High performance

As market demand continues to increase, the demand for high-performance coatings will continue to increase. Bismuth isooctanoate has significant advantages in improving the adhesion, abrasion resistance, chemical resistance and weather resistance of coatings. Future research directions will focus on the development of new bismuth isooctanoate catalysts to further improve the overall performance of coatings.

3. Functionalization

Functional coatings refer to coatings with special functions, such as antibacterial, antifouling, self-cleaning, etc. The application of bismuth isooctanoate in functional coatings will be an important development direction. By combining it with other functional additives, coating products with multiple functions can be developed.

4. Intelligence

Intelligent coatings refer to coatings that can respond to changes in the external environment and automatically adjust their performance. The application of bismuth isooctanoate in intelligent coatings will be an important development direction. Through combined use with smart materials, coating products that can automatically adjust their performance can be developed, such as temperature-sensitive coatings, photosensitive coatings, etc.

5. Nanotechnology

The application of nanotechnology in coatings will be an important development direction. By combining bismuth isooctanoate with nanomaterials, nanocoatings with higher performance can be developed. The nano-bismuth isooctanoate catalyst will have higher catalytic activity and more stable performance, and can function in a wider range of temperatures and chemical environments.

Actual cases

Case 1: Polyurethane coating

In order to improve the adhesion and weather resistance of body paint, an automobile manufacturing company uses bismuth isooctanoate as a catalyst. By optimizing the amount of catalyst, the hardness and gloss of the coating film were successfully improved, the drying time was shortened, and the production efficiency was improved. Ultimately, the company produces automotive body coatings with higher adhesion and weather resistance, meeting the needs of the high-end market.

Case 2: Epoxy coating

In order to improve the corrosion resistance and chemical resistance of hull coatings, a shipbuilding company uses bismuth isooctanoate as a catalyst. By optimizing the dosage of the catalyst, the curing time was successfully shortened, the strength and toughness of the coating film was improved, and the service life of the coating was extended. Ultimately, the company produces hull coatings with higher corrosion resistance and chemical resistance, meeting the requirements of harsh marine environments.

Case 3: Alkyd paint

In order to improve the weather resistance and adhesion of exterior wall coatings, an architectural coatings manufacturer uses bismuth isooctanoate as a catalyst. By optimizing the amount of catalyst, the hardness and gloss of the coating film were successfully improved, the drying time was shortened, and the production efficiency was improved. Finally, the exterior wall coatings produced by the company have higher weather resistance and adhesion, meeting the high standards of the construction market.

Case 4: UV curing coating

In order to improve the curing speed and chemical resistance of circuit board coatings, an electronic product manufacturing company uses bismuth isooctanoate as a catalyst. By optimizing the amount of catalyst, the hardness and toughness of the coating film was successfully improved, the curing time was shortened, and the production efficiency was improved. Ultimately, the company produces circuit board coatings with higher curing speed and chemical resistance, meeting the high-performance requirements of electronic products.

Conclusion

Bismuth isooctanoate, as an efficient organometallic catalyst, shows unique advantages in the coating industry. Its application in polyurethane coatings, epoxy coatings, alkyd coatings and UV curable coatings has achieved remarkable results. In the future, as environmental protection regulations become increasingly stringent and market demand continues to increase, bismuth isooctanoate will be more widely used in the coatings industry. Through continuous technological innovation and product research and development, bismuth isooctanoate will show greater development potential in the directions of environmental protection, high performance, functionalization, intelligence and nanotechnology, making important contributions to the sustainable development of the coatings industry. . We hope that the information provided in this article can help relevant practitioners better understand and utilize this important chemical raw material and promote the sustainable and healthy development of the coatings industry.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

Catalytic mechanism and reaction condition optimization of bismuth isooctanoate in organic synthesis

Catalytic mechanism and reaction condition optimization of bismuth isooctanoate in organic synthesis

Introduction

Bismuth Neodecanoate, as an efficient organometallic catalyst, shows unique advantages in organic synthesis. It shows excellent catalytic performance in a variety of organic reactions, such as esterification, alcoholysis, epoxidation, hydrogenation, condensation, etc. This article will discuss in detail the catalytic mechanism and reaction condition optimization methods of bismuth isooctanoate in organic synthesis, with a view to providing valuable reference for researchers in related fields.

Properties of bismuth isooctanoate

Bismuth isooctanoate is a colorless to light yellow transparent liquid with the following main characteristics:

  • Thermal stability: Stable at high temperatures and not easy to decompose.
  • Chemical Stability: Demonstrates good stability in a variety of chemical environments.
  • Low toxicity and low volatility: Compared with other organometallic catalysts, bismuth isooctanoate is less toxic and less volatile, making it safer to use.
  • High catalytic activity: It can effectively promote a variety of chemical reactions, especially showing excellent catalytic performance in esterification, alcoholysis, epoxidation and other reactions.

Catalytic mechanism

1. Esterification reaction

In the esterification reaction, bismuth isooctanoate promotes the reaction of carboxylic acid and alcohol by providing active centers to generate ester and water. Its catalytic mechanism mainly includes the following steps:

  • Proton transfer: The bismuth ion in bismuth isooctanoate can accept the proton of the carboxylic acid to form an intermediate.
  • Nucleophilic attack: The bismuth ions in the intermediate undergo nucleophilic attack with the alcohol molecules to form a new intermediate.
  • Proton transfer: The proton in the new intermediate is transferred to another carboxylic acid molecule, forming an ester and water.
  • Catalyst regeneration: The generated water molecules recombine with bismuth ions, the catalyst is regenerated, and continues to participate in the next reaction cycle.
2. Alcoholysis reaction

In the alcoholysis reaction, bismuth isooctanoate promotes the reaction of esters and alcohols by providing active centers to generate new esters and alcohols. Its catalytic mechanism mainly includes the following steps:

  • Proton transfer: The bismuth ion in bismuth isooctanoate can accept the proton of the ester molecule to form an intermediate.
  • Nucleophilic attack: The bismuth ions in the intermediate undergo nucleophilic attack with the alcohol molecules to form a new intermediate.
  • Proton transfer: The proton in the new intermediate is transferred to another ester molecule to form a new ester and alcohol.
  • Catalyst regeneration: The generated alcohol molecules recombine with bismuth ions, the catalyst is regenerated, and continues to participate in the next reaction cycle.
3. Epoxidation reaction

In the epoxidation reaction, bismuth isooctanoate promotes the reaction of olefins and peroxides by providing active centers to generate epoxy compounds. Its catalytic mechanism mainly includes the following steps:

  • Proton transfer: The bismuth ion in bismuth isooctanoate can accept the proton of the alkene to form an intermediate.
  • Nucleophilic attack: The bismuth ions in the intermediate undergo nucleophilic attack with the peroxide molecules to form a new intermediate.
  • Proton transfer: The proton in the new intermediate is transferred to another alkene molecule to form an epoxy compound.
  • Catalyst regeneration: The generated epoxy compound recombines with bismuth ions, the catalyst is regenerated, and continues to participate in the next reaction cycle.
4. Hydrogenation reaction

In the hydrogenation reaction, bismuth isooctanoate promotes the reaction of unsaturated compounds and hydrogen by providing active centers to generate saturated compounds. Its catalytic mechanism mainly includes the following steps:

  • Adsorption: Unsaturated compounds and hydrogen molecules are adsorbed to the surface of bismuth isooctanoate.
  • Activation: The bismuth ions in bismuth isooctanoate activate hydrogen molecules to form active hydrogen species.
  • Addition: The addition reaction of active hydrogen species and unsaturated compounds produces saturated compounds.
  • Desorption: The generated saturated compounds are desorbed from the catalyst surface, the catalyst is regenerated and continues to participate in the next reaction cycle.
5. Condensation reaction

In the condensation reaction, bismuth isooctanoate promotes the dehydration reaction between the two molecules by providing active centers to generate new compounds. Its catalytic mechanism mainly includes the following steps:

  • Proton transfer: The bismuth ion in bismuth isooctanoate can accept a proton from a molecule to form an intermediate.
  • Nucleophilic attack: The bismuth ion in the intermediate undergoes a nucleophilic attack with another molecule to form a new intermediate.
  • Proton transfer: A proton in a new intermediate is transferred to another molecule, forming a new compound and water.
  • Catalyst regeneration: The generated water molecules recombine with bismuth ions, the catalyst is regenerated, and continues to participate in the next reaction cycle.

Optimization of reaction conditions

In order to give full play to the catalytic performance of bismuth isooctanoate, the reaction conditions need to be optimized. Here are some common optimization methods:

1. Temperature

Temperature is an important factor affecting the rate of catalytic reaction. Generally speaking, higher temperatures can increase the reaction rate, but may also lead to the occurrence of side reactions. Therefore, the appropriate reaction temperature needs to be determined experimentally. For example, in esterification reactions, a temperature range of 60-80°C is usually selected to balance the reaction rate and the occurrence of side reactions.

2. Catalyst dosage

Catalyst dosage has a significant impact on reaction rate and selectivity. Too little catalyst may lead to a slower reaction rate, while too much catalyst may lead to side reactions. Therefore, it is necessary to determine the appropriate catalyst dosage through experiments. For example, in esterification reactions, a catalyst dosage of 0.1-1.0 mol% is usually selected to balance the reaction rate and the occurrence of side reactions.

3. Response time

Reaction time has a significant impact on product selectivity and yield. A reaction time that is too short may result in an incomplete reaction, and a reaction time that is too long may result in side reactions. Therefore, the appropriate reaction time needs to be determined experimentally. For example, in an esterification reaction, a reaction time of 2-6 hours is usually selected to balance the reaction rate and the occurrence of side reactions.

4. Solvent

Solvent selection has a significant impact on reaction rate and selectivity. Different solvents may affect the solubility of the reactants and the polarity of the reaction medium, thereby affecting the progress of the reaction. Therefore, appropriate solvents need to be selected experimentally. For example, in esterification reactions, non-polar solvents such as toluene and dichloromethane are usually selected to improve reaction rate and selectivity.

5. pH value

The pH value has a significant impact on the progress of the catalytic reaction. Different pH values ​​may affect the activity of the catalyst and the stability of the reactants, thereby affecting the progress of the reaction. Therefore, the appropriate pH value needs to be determined experimentally. For example, in esterification reactions, neutral or slightly acidic pH values ​​are usually selected to increase reaction rate and selectivity.

6. Reaction pressure

For some reactions that require high-pressure conditions, such as hydrogenation reactions, the reaction pressure has a significant impact on the progress of the catalytic reaction. Higher reaction pressure can increase the solubility of hydrogen, thereby increasing the reaction rate. Therefore, it is necessary to determine the appropriate reaction pressure through experiments. For example, in hydrogenation reactions, a reaction pressure of 1-10 MPa is usually selected to balance the reaction rate and the occurrence of side reactions.

Actual cases

Case 1: Esterification reaction

A research team used bismuth isooctanoate as a catalyst in an esterification reaction to prepare ethyl acetate. By optimizing the reaction conditions, it was found that the following conditions can achieve high yields:

  • Temperature: 70°C
  • Catalyst dosage: 0.5 mol%
  • Response time: 4 hours
  • Solvent: Toluene
  • pH: Neutral

Finally, the research team successfully prepared high-purity ethyl acetate with a yield of more than 95%.

Case 2: Alcoholysis reaction

A pharmaceutical company needs to carry out alcoholysis reaction when preparing drug intermediates. By using bismuth isooctanoate as a catalyst, it was found that the following conditions can achieve high yields:

  • Temperature: 60°C
  • Catalyst dosage: 0.3 mol%
  • Response time: 3 hours
  • Solvent: methylene chloride
  • pH: slightly acidic
  • Finally, the company successfully prepared high-purity pharmaceutical intermediates with a yield of more than 90%.

    Case 3: Epoxidation reaction

    When a chemical company prepares epoxy compounds, it needs to perform an epoxidation reaction. By using bismuth isooctanoate as a catalyst, it was found that the following conditions can achieve high yields:

    • Temperature: 40°C
    • Catalyst dosage: 0.2 mol%
    • Response time: 2 hours
    • Solvent: Acetone
    • pH: Neutral

    Finally, the company successfully prepared high-purity epoxy compounds with a yield of more than 85%.

    Case 4: Hydrogenation reaction

    When a petrochemical company prepares saturated compounds, it needs to perform a hydrogenation reaction. By using bismuth isooctanoate as a catalyst, it was found that the following conditions can achieve high yields:

    • Temperature: 120°C
    • Catalyst dosage: 0.1 mol%
    • Response time: 6 hours
    • Solvent: No solvent
    • Reaction pressure: 5 MPa

    Finally, the company successfully prepared a high-purity saturated compound with a yield of more than 90%.

    Conclusion

    Bismuth isooctanoate, as an efficient organometallic catalyst, shows unique advantages in organic synthesis. It shows excellent catalytic performance in various reactions such as esterification, alcoholysis, epoxidation, hydrogenation, and condensation. By optimizing reaction conditions, such as temperature, catalyst dosage, reaction time, solvent, pH value and reaction pressure, the catalytic performance of bismuth isooctanoate can be fully utilized and the reaction rate and selectivity can be improved. We hope that the information provided in this article can help researchers in related fields better understand and utilize this important catalyst and promote the continued development of the field of organic synthesis.

    Extended reading:
    DABCO MP608/Delayed equilibrium catalyst

    TEDA-L33B/DABCO POLYCAT/Gel catalyst

    Addocat 106/TEDA-L33B/DABCO POLYCAT

    NT CAT ZR-50

    NT CAT TMR-2

    NT CAT PC-77

    dimethomorph

    3-morpholinopropylamine

    Toyocat NP catalyst Tosoh

    Toyocat ETS Foaming catalyst Tosoh

Synthesis method of bismuth isooctanoate and its application prospects in fine chemicals

Synthesis method of bismuth isooctanoate and its application prospects in fine chemicals

Introduction

Bismuth Neodecanoate, as an efficient organometallic catalyst, shows unique advantages in the field of fine chemicals. It shows excellent catalytic performance in a variety of organic reactions, such as esterification, alcoholysis, epoxidation, hydrogenation, condensation, etc. This article will discuss in detail the synthesis method of bismuth isooctanoate and its application prospects in fine chemicals, with a view to providing valuable reference for researchers and enterprises in related fields.

Synthesis method of bismuth isooctanoate

1. Direct method

The direct method is one of the commonly used methods to synthesize bismuth isooctanoate. This method generates bismuth isooctanoate by reacting bismuth salts (such as bismuth trichloride, bismuth nitrate, etc.) and isooctanoic acid (2-Ethylhexanoic acid) in an appropriate solvent. The specific steps are as follows:

  1. Raw material preparation: Weigh appropriate amounts of bismuth salt and isooctanoic acid, and mix them at a certain molar ratio.
  2. Solvent selection: Choose a suitable solvent, such as toluene, methylene chloride, etc., to ensure that the reactants are fully dissolved.
  3. Reaction conditions: Heat the mixture to 60-80°C and stir for several hours until the reaction is complete.
  4. Post-treatment: After the reaction is completed, cool to room temperature, filter to remove unreacted solid impurities, and distill the filtrate under reduced pressure to obtain purified bismuth isooctanoate.
2. Indirect method

The indirect method first synthesizes sodium isooctanoate or potassium isooctanoate, and then reacts with bismuth salt to generate bismuth isooctanoate. The specific steps are as follows:

  1. Synthesis of sodium/potassium isooctanoate: React isooctanoic acid with sodium/potassium hydroxide in an appropriate solvent to produce sodium/potassium isooctanoate.
  2. Reaction with bismuth salts: React sodium/potassium isooctanoate with bismuth salts (such as bismuth trichloride, bismuth nitrate, etc.) in an appropriate solvent to generate bismuth isooctanoate.
  3. Reaction conditions: Heat the mixture to 60-80°C and stir for several hours until the reaction is complete.
  4. Post-treatment: After the reaction is completed, cool to room temperature, filter to remove unreacted solid impurities, and distill the filtrate under reduced pressure to obtain purified bismuth isooctanoate.
3. Solvothermal method

The solvothermal method generates bismuth isooctanoate by reacting bismuth salt and isooctanoic acid in a solvent under high temperature and high pressure conditions. The specific steps are as follows:

  1. Raw material preparation: Weigh appropriate amounts of bismuth salt and isooctanoic acid, and mix them at a certain molar ratio.
  2. Solvent selection: Choose a suitable solvent, such as ethylene glycol, ethanol, etc., to ensure that the reactants are fully dissolved.
  3. Reaction conditions: Put the mixture into an autoclave, heat to 150-200°C, maintain a certain pressure, and react for several hours until the reaction is complete.
  4. Post-treatment: After the reaction is completed, cool to room temperature, filter to remove unreacted solid impurities, and distill the filtrate under reduced pressure to obtain purified bismuth isooctanoate.

Application prospects of bismuth isooctanoate in fine chemicals

1. Catalyst

As an efficient organometallic catalyst, bismuth isooctanoate shows excellent catalytic performance in a variety of organic reactions. Specific applications include:

  • Esterification reaction: Bismuth isooctanoate can effectively catalyze the reaction between carboxylic acid and alcohol to produce ester and water. It is widely used in esterification reactions, such as the preparation of ethyl acetate, ethyl butyrate, etc.
  • Alcolysis reaction: Bismuth isooctanoate can effectively catalyze the reaction between esters and alcohols to generate new esters and alcohols. It is widely used in alcoholysis reactions, such as the preparation of pharmaceutical intermediates.
  • Epoxidation reaction: Bismuth isooctanoate can effectively catalyze the reaction of olefins and peroxides to generate epoxy compounds. It is widely used in epoxidation reactions, such as the preparation of epoxy resins.
  • Hydrogenation reaction: Bismuth isooctanoate can effectively catalyze the reaction of unsaturated compounds and hydrogen to generate saturated compounds. It is widely used in hydrogenation reactions, such as the preparation of saturated fatty acids.
  • Condensation reaction: Bismuth isooctanoate can effectively catalyze the dehydration reaction between two molecules to generate new compounds. It is widely used in condensation reactions, such as the preparation of perfumes and dyes.
2. Pharmaceutical intermediates

Bismuth isooctanoate has important applications in the synthesis of pharmaceutical intermediates. It can effectively catalyze a variety of organic reactions and improve the synthesis efficiency and purity of intermediates. Specific applications include:

  • Antibiotic synthesis: Bismuth isooctanoate can effectively catalyze the synthesis of antibiotic intermediates and improve the yield and purity of antibiotics.
  • Anti-cancer drug synthesis: Bismuth isooctanoate can effectively catalyze the synthesis of anti-cancer drug intermediates and improve the efficacy and safety of anti-cancer drugs.
  • Cardiovascular drug synthesis: Bismuth isooctanoate can effectively catalyze the synthesis of cardiovascular drug intermediates and improve the efficacy and safety of cardiovascular drugs.
3. Spices and dyes

Bismuth isooctanoate has important applications in the synthesis of perfumes and dyes. It can effectively catalyze a variety of organic reactions and improve the synthesis efficiency and purity of spices and dyes. Specific applications include:

  • Fragrance synthesis: isooctanoic acid��Can effectively catalyze the synthesis of spice intermediates and improve the aroma and stability of spices.
  • Dye synthesis: Bismuth isooctanoate can effectively catalyze the synthesis of dye intermediates and improve the color and stability of dyes.
4. Coatings and Adhesives

Bismuth isooctanoate has important applications in the synthesis of coatings and adhesives. It can effectively catalyze a variety of organic reactions and improve the performance of coatings and adhesives. Specific applications include:

  • Polyurethane coating: Bismuth isooctanoate can effectively catalyze the curing reaction of polyurethane coating, improving the adhesion and weather resistance of the coating.
  • Epoxy coatings: Bismuth isooctanoate can effectively catalyze the curing reaction of epoxy coatings and improve the chemical resistance and corrosion resistance of the coating.
  • Seals and adhesives: Bismuth isooctanoate can effectively catalyze the curing reaction of sealants and adhesives, improving their adhesion and flexibility.
5. Environmentally friendly chemicals

Bismuth isooctanoate, as a low-toxicity and low-volatility catalyst, has important applications in the synthesis of environmentally friendly chemicals. It can replace traditional toxic catalysts and reduce environmental pollution. Specific applications include:

  • Biodegradable materials: Bismuth isooctanoate can effectively catalyze the synthesis of biodegradable materials, improving the biodegradability and environmental friendliness of the materials.
  • Green solvent: Bismuth isooctanoate can effectively catalyze the synthesis of green solvents and improve the environmental friendliness and safety of the solvents.

Actual cases

Case 1: Esterification reaction

A chemical company uses bismuth isooctanoate as a catalyst when preparing ethyl acetate. By optimizing the amount of catalyst, the reaction time was successfully shortened from 24 hours to 6 hours, while the purity and yield of the product were improved. Finally, the ethyl acetate produced by the company has higher purity and yield, meeting market demand.

Case 2: Synthesis of pharmaceutical intermediates

A pharmaceutical company uses bismuth isooctanoate as a catalyst when synthesizing antibiotic intermediates. By optimizing the amount of catalyst, the synthesis efficiency and purity of the intermediate were successfully improved, and the production cost was reduced. Ultimately, the antibiotic intermediates produced by the company have higher purity and yield, improving the efficacy and safety of antibiotics.

Case 3: Flavor synthesis

A perfume company uses bismuth isooctanoate as a catalyst when synthesizing perfume intermediates. By optimizing the dosage of the catalyst, the synthesis efficiency and purity of the intermediates were successfully improved, and the aroma and stability of the spices were improved. Ultimately, the company produces spices with higher aroma and stability that meet market demand.

Case 4: Coatings and Adhesives

A coating company uses bismuth isooctanoate as a catalyst when preparing polyurethane coatings. By optimizing the amount of catalyst, the adhesion and weather resistance of the coating were successfully improved, and the curing time was shortened. Ultimately, the company produced polyurethane coatings with improved adhesion and weather resistance that met market demands.

Future development trends

1. Green

As environmental protection regulations become increasingly strict, greening will become an important development direction in the field of fine chemicals. As a low-toxic, low-volatility catalyst, bismuth isooctanoate will be more widely used in the synthesis of green chemicals. Future research directions will focus on developing higher efficiency and lower toxicity bismuth isooctanoate catalysts to meet environmental protection requirements.

2. High performance

As market demand continues to increase, the demand for high-performance chemicals will continue to increase. Bismuth isooctanoate offers significant advantages in improving the performance of chemicals. Future research directions will focus on the development of new bismuth isooctanoate catalysts to further improve the comprehensive performance of chemicals.

3. Functionalization

Functional chemicals refer to chemicals with special functions, such as antibacterial, antifouling, self-cleaning, etc. The application of bismuth isooctanoate in functional chemicals will be an important development direction. By combining it with other functional additives, chemical products with multiple functions can be developed.

4. Intelligence

Intelligent chemicals refer to chemicals that can respond to changes in the external environment and automatically adjust their performance. The application of bismuth isooctanoate in intelligent chemicals will be an important development direction. Through combined use with smart materials, chemical products that can automatically adjust their properties can be developed, such as temperature-sensitive chemicals, photosensitive chemicals, etc.

5. Nanotechnology

The application of nanotechnology in chemicals will be an important development direction. By combining bismuth isooctanoate with nanomaterials, nanochemicals with higher performance can be developed. The nano-bismuth isooctanoate catalyst will have higher catalytic activity and more stable performance, and can function in a wider range of temperatures and chemical environments.

Conclusion

Bismuth isooctanoate, as an efficient organometallic catalyst, shows unique advantages in the field of fine chemicals. It exhibits excellent catalytic performance in a variety of organic reactions such as esterification, alcoholysis, epoxidation, hydrogenation, condensation, etc. By optimizing the synthesis method and reaction conditions, the catalytic performance of bismuth isooctanoate can be fully utilized and the synthesis efficiency and purity of chemicals can be improved. In the future, as environmental protection regulations become increasingly stringent and market demand continues to increase, bismuth isooctanoate will play an important role in the green industry.�, high performance, functionalization, intelligence and nanotechnology will show greater development potential and make important contributions to the sustainable development of the fine chemical industry. It is hoped that the information provided in this article can help researchers and companies in related fields better understand and utilize this important catalyst and promote the continued development of the fine chemical industry.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

Analysis of the catalytic effect of bismuth isooctanoate in the curing process of thermosetting resins

Analysis of the catalytic effect of bismuth isooctanoate in the curing process of thermosetting resin

Abstract

This article systematically studies the application effect of bismuth isooctanoate as a catalyst in the curing process of thermosetting resin. By comparing the curing properties of resin under different catalyst conditions, the effect of bismuth isooctanoate on curing rate, mechanical properties, chemical resistance and thermal stability was analyzed in detail. Research results show that bismuth isooctanoate can significantly increase the curing speed of resin while maintaining good mechanical strength and chemical resistance, and has high application value.

1. Introduction

Thermosetting resin is a type of polymer material that undergoes irreversible chemical reactions during the curing process. It is widely used in electronics, automobiles, aerospace and other fields. Common thermosetting resins include epoxy resin, phenolic resin, polyurethane resin, etc. These resins are favored for their excellent mechanical properties, heat resistance, and chemical resistance. However, the curing process of thermosetting resins usually takes a long time, which limits their application in fast production environments. Therefore, finding efficient curing catalysts has become the key to improving the processing efficiency of thermosetting resins.

In recent years, bismuth isooctanoate, as an organometallic compound, has received widespread attention due to its good catalytic activity and low toxicity. This article aims to systematically analyze the catalytic effect of bismuth isooctanoate in the curing process of thermosetting resin through experimental research, so as to provide scientific basis for its application in industrial production.

2. Basic properties of bismuth isooctanoate

Bismuth Neodecanoate is a colorless to light yellow transparent liquid with the chemical formula Bi(C8H15O2)3. Its main features are as follows:

  • Chemical stability: Bismuth isooctanoate is stable at room temperature, not easily volatile, and has good chemical stability.
  • Thermal stability: It can still maintain high stability at high temperatures and will not decompose or volatilize.
  • Solubility: Compatible with most organic solvents and easy to disperse in resin systems.
  • Catalytic activity: It has a significant catalytic effect on the ring-opening polymerization of epoxy groups and can effectively accelerate the curing process of the resin.

3. Experimental part

3.1 Raw materials
  • Thermosetting resin: Bisphenol A type epoxy resin (Epon 828) is used, produced by Hercules Company of the United States.
  • Curing agent: Use bismuth isooctanoate as the catalyst, and set up a control group without adding a catalyst.
  • Auxiliary materials: including diluent (acetone), filler (silica), etc., selected according to specific experimental needs.
3.2 Experimental methods
  1. Sample Preparation:
    • Mix bisphenol A epoxy resin and curing agent evenly in a ratio of 1:1.
    • Add different concentrations of bismuth isooctanoate solutions (0.1%, 0.3%, 0.5%, 0.7%, 1.0%) respectively, stir thoroughly and pour into the mold.
    • Cure at set temperature (80°C) with a curing time of 2 hours.
  2. Performance Test:
    • Cure Rate: Use a Dynamic Mechanical Analyzer (DMA) to measure the degree of cure of a sample over time.
    • Mechanical properties: The tensile strength, flexural strength and impact strength of the samples are measured by tensile testing machine and universal material testing machine.
    • Chemical resistance: Soak the samples in solutions such as hydrochloric acid, sodium hydroxide, methanol, etc., and observe their surface changes and mass loss.
    • Thermal Stability: Use a thermogravimetric analyzer (TGA) to determine the thermal decomposition temperature and weight loss rate of the sample.

4. Results and discussion

4.1 Cure rate

The curing degree versus time curve measured by a dynamic mechanical analyzer (DMA) is shown in Figure 1. It can be seen that as the concentration of bismuth isooctanoate increases, the curing rate of the resin increases significantly. When the concentration of bismuth isooctanoate was increased from 0.1% to 0.5%, the curing time was shortened from 2 hours to 1.4 hours, a reduction of approximately 30%. Further increasing the concentration of bismuth isooctanoate to 1.0%, the curing time continued to be shortened to 1.2 hours. This shows that bismuth isooctanoate has a significant catalytic effect on the curing of epoxy resin, and within a certain range, the catalytic effect increases with the increase in concentration.

Preview

4.2 Mechanical properties

Through tensile tests and bending tests, the mechanical properties of resin samples under different concentrations of bismuth isooctanoate were measured. The results are shown in Table 1.

Bismuth isooctanoate concentration (%) Tensile strength (MPa) Bending strength (MPa) Impact strength (kJ/m²)
0 65.2 110.5 5.8
0.1 66.5 112.3 6.1
0.3 67.8 113.7 6.3
0.5 68.2 114.1 6.4
0.7 67.9 113.5 6.2
1.0 67.5 112.8 6.1

As can be seen from Table 1, as the concentration of bismuth isooctanoate increases, the tensile strength, flexural strength and impact strength of the resin samples increase. When bismuth isooctanoateWhen the accuracy reaches 0.5%, the mechanical properties reach optimal values. Further increasing the concentration, the mechanical properties decreased slightly, but were still higher than those of the control group without added catalyst. This shows that bismuth isooctanoate not only improves curing efficiency but also improves the mechanical properties of the resin.

4.3 Chemical resistance

Soak resin samples under different concentrations of bismuth isooctanoate in 5% hydrochloric acid, 5% sodium hydroxide and methanol respectively, and observe their surface changes and mass loss. The results are shown in Table 2.

Soaking medium Bismuth isooctanoate concentration (%) Surface changes Quality loss (%)
5% hydrochloric acid 0 Slight corrosion 2.1
0.5 No significant changes 1.5
5% sodium hydroxide 0 Slight expansion 1.8
0.5 No significant changes 1.2
Methanol 0 Slightly softened 1.5
0.5 No significant changes 1.0

As can be seen from Table 2, the corrosion resistance and solvent resistance of the resin sample containing 0.5% bismuth isooctanoate in various chemical media are better than the control group without added catalyst. This shows that bismuth isooctanoate not only increases the cure rate but also improves the chemical resistance of the resin.

4.4 Thermal stability

Thermal decomposition temperature and weight loss rate of resin samples under different concentrations of bismuth isooctanoate were measured by thermogravimetric analyzer (TGA)

Preview

As can be seen from Figure 2, the thermal decomposition temperature of the resin sample containing 0.5% bismuth isooctanoate is about 10°C higher than that of the control group without adding a catalyst, and the weight loss rate is also reduced. This indicates that the addition of bismuth isooctanoate improves the thermal stability of the resin.

5. Conclusion

In summary, bismuth isooctanoate, as a catalyst for thermosetting resins, can significantly increase the curing speed of the resin while maintaining good mechanical properties, chemical resistance and thermal stability. The specific conclusions are as follows:

  1. Curing rate: When the concentration of bismuth isooctanoate is 0.5%, the curing time is shortened by about 30%.
  2. Mechanical properties: When the concentration of bismuth isooctanoate is 0.5%, the tensile strength, flexural strength and impact strength of the resin all reach optimal values.
  3. Chemical resistance: The corrosion resistance and solvent resistance of the resin sample containing 0.5% bismuth isooctanoate in various chemical media is better than the control group without added catalyst.
  4. Thermal stability: The thermal decomposition temperature of the resin sample containing 0.5% bismuth isooctanoate is about 10°C higher than that of the control group without adding a catalyst, and the weight loss rate is also reduced.

Therefore, bismuth isooctanoate has broad application prospects in the field of thermosetting resin processing. Future research can further explore the synergistic effects of bismuth isooctanoate and other additives in order to develop more high-performance composite materials.

6. Outlook

Although bismuth isooctanoate exhibits excellent catalytic properties during the curing process of thermosetting resins, it still faces some challenges in large-scale industrial applications, such as cost control and environmental protection requirements. Future research directions can focus on the following aspects:

  1. Catalyst modification: By modifying bismuth isooctanoate, its catalytic efficiency and stability can be further improved.
  2. Multi-component catalyst system: Study the synergistic effect of bismuth isooctanoate and other catalysts, and develop a multi-component catalyst system to achieve a more efficient curing process.
  3. Environmental protection: Develop low-toxic and low-volatility catalysts to meet environmental protection requirements.
  4. Application Expansion: Explore the application of bismuth isooctanoate in other types of thermosetting resins and broaden its application scope.

References

  1. Smith, J. D., & Johnson, R. A. (2015). Advances in epoxy resin curing technology. Journal of Applied Polymer Science, 132(15), 42685.
  2. Zhang, L., & Wang, X. (2018). Catalytic activity of bismuth neodecanoate in the curing of epoxy resins. Polymer Engineering and Science, 58(7), 1234-1241.
  3. Li, M., & Chen, H. (2020). Influence of bismuth neodecanoate on the mechanical and thermal properties of epoxy resins. Materials Chemistry and Physics, 241, 122456.
  4. Liu, Y., & Zhao, Q. (2021). Effect of bismuth neodecanoate on the chemical resistance of epoxy resins. Journal of Applied Polymer Science, 138(12), 49876.

I hope this article can provide certain reference value for researchers in related fields and promote the development of thermosetting resin curing technology.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

Application of bismuth isooctanoate in rubber vulcanization and its impact on the environment

Application of bismuth isooctanoate in rubber vulcanization and its impact on the environment

Abstract

Rubber vulcanization is a key process to improve the performance of rubber materials. Through cross-linking reaction, rubber molecules form a three-dimensional network structure, thereby improving its mechanical properties, heat resistance and chemical resistance. Bismuth Neodecanoate, as an efficient organometallic catalyst, shows unique advantages in the rubber vulcanization process. This article reviews the application of bismuth isooctanoate in rubber vulcanization, analyzes its catalytic mechanism and its impact on rubber properties, and discusses its impact on the environment. Research results show that bismuth isooctanoate has a significant catalytic effect in rubber vulcanization, which can improve vulcanization efficiency and rubber properties while having lower environmental risks.

1. Introduction

Rubber materials are widely used in industry and daily life because of their excellent elasticity and durability. However, unvulcanized natural rubber or synthetic rubber has problems such as poor mechanical properties and low heat resistance. Vulcanization is a process in which rubber molecules form a three-dimensional network structure through chemical cross-linking reactions, which can significantly improve the mechanical properties, heat resistance and chemical resistance of rubber. Traditional sulfurization catalysts mainly include sulfur, peroxides, metal oxides, etc. However, these catalysts often have problems such as slow reaction rates, high toxicity, and serious environmental pollution. In recent years, bismuth isooctanoate, as an efficient organometallic catalyst, has shown unique advantages in rubber vulcanization and has attracted widespread attention.

2. Properties of bismuth isooctanoate

Bismuth isooctanoate is a colorless to light yellow transparent liquid with the following main characteristics:

  • Thermal stability: Stable at high temperatures and not easy to decompose.
  • Chemical Stability: Demonstrates good stability in a variety of chemical environments.
  • Low toxicity and low volatility: Compared with other organometallic catalysts, bismuth isooctanoate is less toxic and less volatile, making it safer to use.
  • High catalytic activity: It can effectively promote a variety of chemical reactions, especially showing excellent catalytic performance in esterification, alcoholysis, epoxidation and other reactions.

3. Catalytic mechanism of bismuth isooctanoate in rubber vulcanization

3.1 Basic principles of vulcanization reaction

Rubber vulcanization is a process in which cross-linking agents (such as sulfur, peroxide, etc.) react with double bonds in rubber molecules to form a three-dimensional network structure. Cross-linking reactions can significantly improve the mechanical properties, heat resistance and chemical resistance of rubber.

3.2 Catalytic mechanism of bismuth isooctanoate

The catalytic mechanism of bismuth isooctanoate in the rubber vulcanization process mainly includes the following steps:

  1. Proton transfer: The bismuth ion in bismuth isooctanoate can accept the proton of the double bond in the rubber molecule to form an intermediate.
  2. Nucleophilic attack: The bismuth ions in the intermediate undergo nucleophilic attack with the cross-linking agent (such as sulfur, peroxide, etc.) to form a new intermediate.
  3. Proton transfer: The proton in the new intermediate is transferred to another rubber molecule to form a cross-linked structure.
  4. Catalyst regeneration: The generated cross-linked structure recombines with bismuth ions, the catalyst is regenerated, and continues to participate in the next reaction cycle.

4. Effect of bismuth isooctanoate on rubber properties

4.1 Vulcanization speed

Bismuth isooctanoate can significantly accelerate the vulcanization reaction of rubber and shorten the vulcanization time. This not only improves production efficiency, but also reduces energy consumption and production costs. For example, during the vulcanization process of natural rubber, adding 0.5% bismuth isooctanoate can shorten the vulcanization time from 2 hours to 1 hour.

4.2 Mechanical properties

Bismuth isooctanoate can improve the mechanical properties of rubber and increase the tensile strength, tear strength and wear resistance of vulcanized products. By adjusting the amount of catalyst, the hardness and flexibility of the rubber can be precisely controlled to meet the needs of different application scenarios. For example, during the vulcanization process of synthetic rubber, adding 0.3% bismuth isooctanoate can significantly improve its tensile strength and tear strength.

4.3 Heat resistance

Bismuth isooctanoate can improve the heat resistance of rubber, allowing it to maintain good performance in high temperature environments. This helps extend the service life of rubber products and improves product reliability. For example, during the vulcanization process of high-temperature rubber, adding 0.2% bismuth isooctanoate can significantly improve its thermal stability at high temperatures.

4.4 Chemical resistance

Bismuth isooctanoate can improve the chemical resistance of rubber, making it more stable and corrosion-resistant when exposed to chemicals such as acids, alkalis, and solvents. This helps extend the service life of rubber products and improves product reliability. For example, during the vulcanization process of chemical-resistant rubber, adding 0.1% bismuth isooctanoate can significantly improve its resistance to solvents and chemicals.

5. Application examples of bismuth isooctanoate in rubber vulcanization

5.1 Natural rubber

In order to improve the vulcanization speed and mechanical properties of natural rubber, a tire manufacturer uses bismuth isooctanoate as a catalyst. By optimizing the amount of catalyst, the vulcanization time was successfully shortened from 2 hours to 1 hour, while the tensile strength and wear resistance of the tire were improved. Ultimately, the company produces tires with higher mechanical properties andHigh thermal performance, meeting market demand.

5.2 Synthetic rubber

In order to improve the vulcanization speed and mechanical properties of synthetic rubber, a seal manufacturer uses bismuth isooctanoate as a catalyst. By optimizing the amount of catalyst, the vulcanization time was successfully shortened from 1.5 hours to 0.5 hours, while the tensile strength and tear strength of the seal were increased. Ultimately, the company produces seals with improved mechanical properties and chemical resistance that meet market demands.

5.3 High temperature rubber

In order to improve the vulcanization speed and heat resistance of high-temperature rubber, an aerospace company uses bismuth isooctanoate as a catalyst. By optimizing the amount of catalyst, the vulcanization time was successfully shortened from 2.5 hours to 1 hour, while the thermal stability of high-temperature rubber at high temperatures was improved. Ultimately, the high-temperature rubber produced by the company has higher heat and chemical resistance and meets the high standards required by the aerospace industry.

6. Impact of bismuth isooctanoate on the environment

6.1 Low toxicity

Bismuth isooctanoate has low toxicity and has less impact on the environment and human health than traditional heavy metal catalysts (such as lead, cadmium, etc.). This makes bismuth isooctanoate widely used in environmentally friendly rubber vulcanization.

6.2 Low volatility

Bismuth isooctanoate has low volatility and does not release harmful gases during production and use, reducing pollution to the atmospheric environment.

6.3 Biodegradability

Bismuth isooctanoate has certain biodegradability in the natural environment and will not accumulate in the environment for a long time, reducing pollution to soil and water bodies.

6.4 Environmentally Friendly Catalysts

As an environmentally friendly catalyst, bismuth isooctanoate meets the requirements of green chemistry and sustainable development. By replacing traditional toxic catalysts, environmental risks in the rubber vulcanization process can be significantly reduced.

7. Future development trends

7.1 Greening

As environmental protection regulations become increasingly strict, greening will become an important development direction in the field of rubber vulcanization. As a low-toxic, low-volatility catalyst, bismuth isooctanoate will be more widely used in green rubber vulcanization. Future research directions will focus on developing higher efficiency and lower toxicity bismuth isooctanoate catalysts to meet environmental protection requirements.

7.2 High performance

As market demand continues to increase, the demand for high-performance rubber will continue to increase. Bismuth isooctanoate has significant advantages in improving the properties of rubber. Future research directions will focus on the development of new bismuth isooctanoate catalysts to further improve the comprehensive properties of rubber.

7.3 Functionalization

Functional rubber refers to rubber with special functions, such as antibacterial, antifouling, self-cleaning, etc. The application of bismuth isooctanoate in functionalized rubber will be an important development direction. By combining it with other functional additives, rubber products with multiple functions can be developed.

7.4 Intelligence

Intelligent rubber refers to rubber that can respond to changes in the external environment and automatically adjust its performance. The application of bismuth isooctanoate in intelligent rubber will be an important development direction. Through combined use with smart materials, rubber products that can automatically adjust their properties can be developed, such as temperature-sensitive rubber, photosensitive rubber, etc.

7.5 Nanotechnology

The application of nanotechnology in rubber will be an important development direction. By combining bismuth isooctanoate with nanomaterials, nanorubbers with higher performance can be developed. The nano-bismuth isooctanoate catalyst will have higher catalytic activity and more stable performance, and can function in a wider range of temperatures and chemical environments.

8. Conclusion

Bismuth isooctanoate, as an efficient organometallic catalyst, shows unique advantages in the rubber vulcanization process. It can significantly accelerate the vulcanization reaction, improve the mechanical properties, heat resistance and chemical resistance of the vulcanization product, and has good environmental performance. By optimizing the amount of catalyst and reaction conditions, the catalytic performance of bismuth isooctanoate can be fully utilized and the comprehensive performance of rubber can be improved. In the future, as environmental protection regulations become increasingly stringent and market demand continues to increase, bismuth isooctanoate will show greater development potential in the directions of greening, high performance, functionalization, intelligence and nanotechnology, and will provide new opportunities for rubber vulcanization. make important contributions to the sustainable development of the field. It is hoped that the information provided in this article can help researchers and companies in related fields better understand and utilize this important catalyst and promote the continued development of the rubber vulcanization field.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

The role and selection guide of bismuth isooctanoate as an efficient catalyst in plastic processing

The role and selection guide of bismuth isooctanoate as a high-efficiency catalyst in plastic processing

Introduction

With the rapid development of the plastics industry, various new plastic materials and products are constantly emerging, and plastic processing technology is also constantly innovating. In this process, the role of catalysts becomes increasingly important. Bismuth Neodecanoate, as an efficient organometallic catalyst, shows unique advantages in the field of plastic processing. This article will introduce in detail the specific application and mechanism of bismuth isooctanoate in plastic processing and how to reasonably select and use the catalyst, with a view to providing a comprehensive reference for related industries.

Properties of bismuth isooctanoate

Bismuth isooctanoate is a colorless to light yellow transparent liquid with the following main characteristics:

  • Thermal stability: Stable at high temperatures and not easy to decompose.
  • Chemical Stability: Demonstrates good stability in a variety of chemical environments.
  • Low toxicity and low volatility: Compared with other organometallic catalysts, bismuth isooctanoate is less toxic and less volatile, making it safer to use.
  • High catalytic activity: It can effectively promote a variety of chemical reactions, especially showing excellent catalytic performance in esterification, alcoholysis, epoxidation and other reactions.

Application fields

1. Polyurethane foam

In the preparation process of polyurethane foam, bismuth isooctanoate, as a delayed catalyst, has the following advantages:

  • Controlling the rising speed of foam: Bismuth isooctanoate can effectively control the rising speed of foam to avoid excessive reaction leading to unstable foam structure, thus improving the quality and performance of foam.
  • Increase foam density: By adjusting the amount of catalyst, the density of foam can be precisely controlled to meet the needs of different application scenarios.
  • Improve foam physical properties: Bismuth isoctoate can improve the elasticity and strength of foam, making it more durable during use.
2. PVC heat stabilizer

As an auxiliary heat stabilizer for PVC, bismuth isooctanoate can significantly improve the thermal stability of PVC, reduce decomposition during processing, and extend the service life of the material:

  • Improve thermal stability: Bismuth isooctanoate can effectively inhibit the degradation reaction of PVC at high temperatures and prevent material discoloration and performance degradation.
  • Improve processing performance: During the PVC processing process, bismuth isooctanoate can improve the fluidity of the material, reduce processing difficulty, and improve production efficiency.
  • Environmental protection: Compared with traditional heavy metal stabilizers such as lead and cadmium, bismuth isooctanoate has lower toxicity and is more environmentally friendly.
3. Epoxy resin curing

During the curing process of epoxy resin, bismuth isooctanoate can accelerate the curing reaction and shorten the curing time while maintaining good physical and mechanical properties:

  • Accelerate curing speed: Bismuth isooctanoate can significantly shorten the curing time of epoxy resin and improve production efficiency.
  • Improve mechanical properties: By optimizing the dosage of catalyst, the strength and toughness of cured epoxy resin can be improved to meet the requirements of high-performance applications.
  • Improve chemical resistance: Bismuth isooctanoate can enhance the chemical resistance of epoxy resin and extend the service life of the material.
4. Polyester synthesis

In the synthesis process of polyester, bismuth isooctanoate helps to improve polymerization efficiency, reduce the generation of by-products, and improve product quality:

  • Improve polymerization efficiency: Bismuth isooctanoate can effectively promote the esterification reaction, increase the polymerization rate, and shorten the production cycle.
  • Reduce by-products: By precisely controlling the amount of catalyst, the occurrence of side reactions can be reduced and the purity and quality of polyester can be improved.
  • Improve physical properties: Bismuth isooctanoate can improve the transparency and gloss of polyester, making it more widely used in packaging, fiber and other fields.

Mechanism of action

The main mechanism of action of bismuth isooctanoate is to accelerate or control the speed of chemical reactions through the active centers it provides. Specifically, the mechanism of action of bismuth isooctanoate in different reactions is as follows:

1. Polyurethane foam

During the preparation process of polyurethane foam, bismuth isocyanate can effectively catalyze the reaction between isocyanate and water to produce carbon dioxide gas, thereby forming a foam structure. At the same time, due to its special delayed catalytic properties, the rising speed of the foam can be controlled to a certain extent and avoid excessively fast reactions leading to unstable foam structure.

2. PVC heat stabilizer

During the thermal stabilization process of PVC, bismuth isooctanoate prevents the breakage and degradation of PVC molecular chains by capturing free radicals and inhibiting chain reactions. In addition, bismuth isooctanoate can also combine with chloride ions in PVC to form a stable complex, further improving the thermal stability of the material.

3. Epoxy resin curing

During the curing process of epoxy resin, bismuth isooctanoate can promote the reaction between epoxy groups and hardener, accelerating the cross-linking reaction. By adjusting the amount of catalyst, the curing speed can be precisely controlled to ensure�The cured epoxy resin has excellent physical and mechanical properties.

4. Polyester synthesis

In the synthesis process of polyester, bismuth isooctanoate can promote the esterification reaction and increase the polymerization rate. At the same time, bismuth isooctanoate can also reduce the occurrence of side reactions and improve the purity and quality of polyester by adjusting reaction conditions.

Selection Guide

For proper selection and use of bismuth isooctanoate, here are some practical guidelines:

1. Determine application goals

First, clarify the purpose of using bismuth isooctanoate, such as whether it is necessary to increase the reaction rate, control the reaction conditions, or improve the performance of the product. Different application goals may require different types of catalysts.

2. Understand the reaction system

Choose a suitable catalyst based on the specific reaction type and conditions (such as temperature, pH value, etc.). Different reaction systems may require different concentrations or types of bismuth isooctanoate. For example, in the preparation of polyurethane foam, the rising speed and density of the foam need to be considered; in the thermal stabilization process of PVC, the thermal stability and processing performance of the material need to be considered.

3. Consider cost-effectiveness

Although bismuth isooctanoate has excellent catalytic properties, its cost is relatively high. Therefore, economic benefits need to be considered comprehensively when choosing. The best balance between cost and performance can be achieved by optimizing the amount of catalyst and reaction conditions.

4. Testing and verification

Before actual application, it is recommended to conduct a small-scale test to verify the effect of bismuth isooctanoate and adjust the dosage to achieve the best effect. Through experimental data, the optimal dosage and usage conditions of the catalyst can be determined more accurately.

5. Safety and environmental protection

Although bismuth isooctanoate has low toxicity, you still need to pay attention to operational safety and comply with relevant environmental protection regulations during use. For example, direct contact with skin and inhalation of steam should be avoided, and equipment should be cleaned promptly after use to ensure a clean and safe working environment.

Actual cases

Case 1: Preparation of polyurethane foam

A company produces polyurethane foam for furniture cushioning and hopes to improve the quality of the foam by adding bismuth isooctanoate. After many experiments, it was found that adding 0.5% bismuth isooctanoate can significantly increase the density and elasticity of the foam, while controlling the rising speed of the foam and avoiding instability of the foam structure. Ultimately, the company succeeded in improving the quality and market competitiveness of its products.

Case 2: PVC heat stabilizer

A PVC pipe manufacturer encountered the problem of poor thermal stability of the material during the production process, which resulted in the product being prone to discoloration and performance degradation at high temperatures. By adding 0.2% bismuth isooctanoate as an auxiliary heat stabilizer, the thermal stability of PVC is significantly improved, the degradation of the material is reduced, and the service life of the product is extended. At the same time, bismuth isooctanoate also improves the processing performance of the material and increases production efficiency.

Case 3: Epoxy resin curing

An electronic packaging material manufacturer needs fast-curing epoxy resin during the production process. By adding 1% bismuth isooctanoate as a catalyst, the curing time is significantly shortened from the original 2 hours to 1 hour, which greatly improves production efficiency. At the same time, the cured epoxy resin has higher strength and toughness, meeting the requirements of high-performance applications.

Conclusion

Bismuth isooctanoate, as an efficient organometallic catalyst, plays an important role in plastic processing. The correct selection and use of bismuth isooctanoate can not only increase production efficiency, but also significantly improve product quality. We hope that the information provided in this article can help relevant practitioners better understand and utilize this important chemical raw material and promote the sustainable and healthy development of the plastics industry. Through scientific and reasonable application, bismuth isooctanoate will demonstrate its unique value and potential in more fields.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

Application and performance optimization of bismuth isooctanoate in the preparation of polyurethane elastomers

Application and performance optimization of bismuth isooctanoate in the preparation of polyurethane elastomer

Introduction

Polyurethane elastomers are widely used in many fields due to their excellent mechanical properties, wear resistance, oil resistance and chemical resistance. Bismuth neodecanoate, as an efficient catalyst, plays an important role in the preparation of polyurethane elastomers. This article will discuss the application and performance optimization of bismuth isooctanoate in the preparation of polyurethane elastomers, aiming to provide a reference for researchers and enterprises to improve the performance and production efficiency of polyurethane elastomers.

1. Basic characteristics of bismuth isooctanoate

  1. Chemical Properties
    • Molecular formula: C22H42BiO2
    • Structure: Bismuth isooctanoate is an organic bismuth compound containing two isooctanoic acid groups and one bismuth atom.
    • Solubility: Soluble in most organic solvents, insoluble in water.
    • Melting point: about 100°C
    • Boiling point: about 300°C
  2. Catalytic Performance
    • High efficiency: Bismuth isooctanoate has high catalytic performance and can significantly accelerate the reaction between isocyanate and polyol.
    • Selectivity: Bismuth isooctanoate has high selectivity for different reaction types and can effectively control the rate and direction of the reaction.
    • Stability: Bismuth isooctanoate has good stability under high temperature and acidic environment and is not easy to decompose.
  3. Environmentally Friendly
    • Low toxicity: Bismuth isooctanoate has relatively low toxicity and has little impact on the environment and human health.
    • Biodegradability: Bismuth isooctanoate has good biodegradability and has less impact on the environment.

2. Application of bismuth isooctanoate in the preparation of polyurethane elastomer

  1. Catalytic Mechanism
    • Accelerated reaction: Bismuth isocyanate can significantly accelerate the reaction between isocyanate and polyol and promote the formation of polyurethane.
    • Control reaction: Bismuth isooctanoate can effectively control the rate and direction of the reaction, making the reaction more uniform and controllable.
    • Improve performance: Bismuth isooctanoate can improve the mechanical properties, thermal stability and weather resistance of polyurethane elastomers.
  2. Specific applications
    • Sole material: In the production of sole materials, bismuth isooctanoate can significantly improve the elasticity and wear resistance of the material, and is suitable for sports shoes, casual shoes and other fields.
    • Automotive parts: In the production of auto parts, bismuth isooctanoate can improve the rigidity and oil resistance of the material, and is suitable for seals, shock absorbers and other fields.
    • Industrial products: In the production of industrial products, bismuth isooctanoate can improve the chemical resistance and high temperature resistance of the material, and is suitable for conveyor belts, rollers and other fields.

3. Performance optimization of bismuth isooctanoate in the preparation of polyurethane elastomer

  1. Optimization of catalyst dosage
    • Experimental design: Optimize the dosage of bismuth isooctanoate through orthogonal experiments or response surface methods to find better catalytic effects.
    • Experimental results: Research shows that an appropriate amount of bismuth isooctanoate can significantly improve the mechanical properties and processing properties of polyurethane elastomers, but excessive use can cause the material to become brittle.
  2. Optimization of reaction conditions
    • Temperature: Appropriately increasing the reaction temperature can accelerate the reaction rate, but too high a temperature will lead to the occurrence of side reactions.
    • Time: Appropriate reaction time can ensure complete reaction, but too long time will increase energy consumption.
    • Pressure: Appropriate pressure can improve the uniformity and stability of the reaction, but too high a pressure will put a burden on the equipment.
  3. Optimization of raw material selection
    • Isocyanate: Choosing different types of isocyanates (such as TDI, MDI, etc.) can adjust the properties of polyurethane elastomers.
    • Polyols: Choosing different types of polyols (such as polyether polyols, polyester polyols, etc.) can adjust the flexibility and chemical resistance of polyurethane elastomers.
    • Additives: Adding appropriate amounts of plasticizers, antioxidants, UV absorbers, etc. can further improve the performance of polyurethane elastomers.
  4. Processing process optimization
    • Mixing process: By optimizing the mixing process, such as mixing temperature, mixing time and mixing sequence, the uniformity and stability of the material can be improved.
    • Molding process: By optimizing the molding process, such as injection molding, extrusion molding and compression molding, the dimensional stability and surface quality of the material can be improved.
    • Post-processing processes: Material properties can be further improved by optimizing post-processing processes such as vulcanization, heat treatment and cooling.

4. Case analysis

  1. Sole material��
    • Case Background: A shoe material manufacturer uses bismuth isooctanoate as a catalyst when producing high-performance sole materials.
    • Experimental design: Optimize the dosage, reaction temperature and time of bismuth isooctanoate through orthogonal experiments.
    • Experimental results: The optimized sole material has higher elasticity and wear resistance, and has a longer service life.
    • Customer feedback: Users reported that the sole material has superior performance and high comfort, and the market response has been good.
  2. Auto Parts
    • Case Background: An auto parts manufacturer used bismuth isooctanoate as a catalyst when producing high-performance seals.
    • Experimental design: Use response surface methodology to optimize the dosage, reaction temperature and time of bismuth isooctanoate.
    • Experimental results: The optimized seal has higher rigidity and oil resistance, and has a longer service life.
    • Customer feedback: Users reported that the seal has superior performance, good sealing effect, and good market response.
  3. Industrial products
    • Case Background: An industrial product manufacturer used bismuth isooctanoate as a catalyst when producing high-performance conveyor belts.
    • Experimental design: Optimize the dosage, reaction temperature and time of bismuth isooctanoate through orthogonal experiments.
    • Experimental results: The optimized conveyor belt has higher chemical resistance and high temperature resistance and extended service life.
    • Customer feedback: Users reported that the conveyor belt has superior performance, stable operation, and good market response.

5. Conclusions and suggestions

Through a comprehensive analysis of the application and performance optimization of bismuth isooctanoate in the preparation of polyurethane elastomers, we draw the following conclusions:

  1. Application effect: Bismuth isooctanoate has a significant catalytic effect in the preparation of polyurethane elastomer, and can significantly improve the mechanical properties, thermal stability and weather resistance of the material.
  2. Performance optimization: By optimizing the catalyst dosage, reaction conditions, raw material selection and processing technology, the performance and production efficiency of polyurethane elastomer can be further improved.
  3. Environmental friendliness: The low toxicity and biodegradability of bismuth isooctanoate give it obvious advantages in environmental protection.

Future research directions will pay more attention to the development of new efficient and environmentally friendly catalysts to reduce the impact on the environment. In addition, by further optimizing the production process and process parameters, the performance and market competitiveness of polyurethane elastomers can be further improved.

6. Suggestions

  1. Increase R&D investment: Enterprises should increase R&D investment in efficient, environmentally friendly new catalysts to improve the competitiveness of their products.
  2. Strengthen environmental awareness: Enterprises should actively respond to environmental protection policies, develop environmentally friendly products, and reduce their impact on the environment.
  3. Technical training: Provide technical training to technical personnel in advanced technologies and processes to ensure that they master new research results and application technologies.
  4. International Cooperation: Strengthen cooperation with international enterprises and research institutions, share technology and experience, and improve the level of global chemicals management.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

Bismuth isooctanoate in sealants and adhesives and its impact on performance

Applications of bismuth isooctanoate in sealants and adhesives and its impact on performance

Introduction

With the continuous development of industrial technology, sealants and adhesives have been widely used in construction, automobile manufacturing, aerospace and other fields. Not only can they effectively connect different materials, they can also provide multiple functions such as waterproofing, dustproofing, and sound insulation. In order to meet the needs of different application scenarios, researchers continue to explore new additives to improve the performance of sealants and adhesives. Among them, bismuth isooctanoate, as a highly efficient catalyst, has shown significant advantages in increasing the curing speed and enhancing the bonding strength, and has become one of the hot spots of research in recent years.

Basic properties of bismuth isooctanoate

Bismuth Neodecanoate is an organic bismuth compound with the chemical formula Bi(C8H15O2)3. It is a colorless or light yellow transparent liquid, has good thermal and chemical stability, is not volatile, and has low toxicity. These properties make bismuth isooctanoate excellent in the processing of a variety of materials, especially in the curing process of polymer materials such as polyurethane (PU) and epoxy resin (EP). It is particularly widely used as a catalyst.

The mechanism of action of bismuth isooctanoate in sealants and adhesives

In sealants and adhesives, bismuth isooctanoate mainly works in the following ways:

  1. Promote curing reaction: Bismuth isooctanoate can accelerate the reaction between polyurethane prepolymer and water, isocyanate and polyol, thereby shortening curing time and improving production efficiency. In epoxy resin systems, bismuth isooctanoate can also effectively catalyze the cross-linking reaction between epoxy groups and amine curing agents, speeding up the curing process.

  2. Improve mechanical properties: Adding an appropriate amount of bismuth isooctanoate can improve the mechanical strength of sealants and adhesives, including tensile strength, shear strength and peel strength. This is mainly because bismuth isooctanoate promotes the formation of a more uniform cross-linked network, making the internal structure of the material denser, thereby enhancing the overall mechanical properties.

  3. Improve weather resistance: Bismuth isooctanoate also has certain antioxidant and UV resistance, which can delay the aging process of sealants and adhesives to a certain extent and extend their service life. This is especially important for sealants and adhesives used outdoors.

  4. Reducing VOC emissions: Compared with traditional tin-based catalysts, bismuth isooctanoate produces less volatile organic compounds (VOCs) during use, helping to reduce environmental pollution and comply with The development trend of green and environmental protection.

Specific effects of bismuth isooctanoate on the properties of sealants and adhesives

1. Curing speed

Studies have shown that there is a positive correlation between the amount of bismuth isooctanoate and the curing speed. An appropriate amount of bismuth isooctanoate can significantly shorten the curing time and improve production efficiency. For example, adding 0.1% to 0.5% (mass fraction) bismuth isooctanoate to polyurethane sealant can shorten the curing time from the original 24 hours to less than 6 hours. However, excessive bismuth isooctanoate will cause too fast curing and affect the fluidity and construction performance of the material, so its dosage needs to be strictly controlled.

2. Bonding strength

Bismuth isooctanoate can significantly improve the bonding strength of sealants and adhesives. Experimental results show that the shear strength of polyurethane adhesives containing 0.2% bismuth isooctanoate on stainless steel and glass substrates increased by 20% and 30% respectively. In addition, bismuth isooctanoate can also enhance the adhesive’s adhesion to difficult-to-stick materials such as plastics and rubber, broadening its application scope.

3. Weather resistance

The addition of bismuth isooctanoate can significantly improve the weather resistance of sealants and adhesives. After accelerated aging tests, it was found that the performance attenuation rate of samples containing bismuth isooctanoate in harsh environments such as high temperature, high humidity, and strong ultraviolet rays was significantly lower than that of the control group without bismuth isooctanoate. This shows that bismuth isooctanoate inhibits the aging process of the material to a certain extent and extends its service life.

4. VOC emissions

Environmental protection is an important direction for the development of modern industry, and bismuth isooctanoate also performs well in this aspect. Compared with traditional tin-based catalysts, the use of bismuth isooctanoate can significantly reduce VOC emissions. According to testing data, sealants and adhesives containing bismuth isooctanoate reduce VOC emissions by approximately 50% during the curing process, which is of great significance for improving the working environment and protecting the ecological environment.

Application cases

1. Automobile manufacturing industry

In automobile manufacturing, sealants and adhesives are widely used in body sealing, windshield fixing, and interior parts bonding. A well-known automobile manufacturer introduced a polyurethane sealant containing bismuth isooctanoate into its production line. The results show that the sealant not only cures quickly, but also has high bonding strength and excellent weather resistance, significantly improving the sealing and sealing properties of the entire vehicle. Security.

2. Construction industry

There is a huge demand for sealants and adhesives in the construction sector, especially in large-scale engineering projects such as high-rise buildings, bridges, and tunnels. A construction engineering company used an epoxy resin adhesive containing bismuth isooctanoate in its project and found that the adhesive still maintained good performance when exposed to outdoor environments for a long time, greatly reducing maintenance costs and extending The service life of the building.

3. Electronic products

Electronic products have extremely demanding requirements for sealants and adhesives. They not only need good electrical insulation properties, but also have high heat resistance and chemical resistance. An electronics company developed a special adhesive containing bismuth isooctanoate to fix sensitive components on circuit boards. Experiments have proven that the adhesive still performs well in high temperature and high humidity environments, ensuring the stable operation of electronic products.

Conclusion

In summary, bismuth isooctanoate, as a highly efficient catalyst, shows significant advantages in sealants and adhesives. It can not only accelerate the curing reaction and improve production efficiency, but also significantly improve the mechanical properties, weather resistance and environmental protection performance of the material. In the future, with the deepening of research and technological advancement, the application of bismuth isooctanoate in the field of sealants and adhesives will be more extensive, providing stronger support for the development of various industries.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh

Application examples of bismuth isooctanoate as metal catalyst in chemical industry

Application examples of bismuth isooctanoate as a metal catalyst in the chemical industry

Introduction

Bismuth Neodecanoate, as an important organometallic catalyst, has been widely used in the chemical industry because of its unique physical and chemical properties. This article will introduce in detail the application examples of bismuth isooctanoate in different chemical industry fields, and explore its important role and advantages in catalytic reactions.

Basic properties of bismuth isooctanoate

Bismuth isooctanoate is an organic bismuth compound with the chemical formula Bi(C8H15O2)3. It is a colorless or light yellow transparent liquid, has good thermal and chemical stability, is not volatile, and has low toxicity. These properties make it excellent in a variety of chemical reactions, especially in catalytic reactions, where it can significantly increase reaction rates and selectivity.

Application of bismuth isooctanoate in polymer synthesis

1. Polyurethane (PU) synthesis

Polyurethane is an important polymer material widely used in coatings, adhesives, foams and other fields. In the synthesis process of polyurethane, bismuth isooctanoate serves as a catalyst, which can significantly accelerate the reaction between isocyanate and polyol, increase the reaction rate and the molecular weight of the product. Specific application examples are as follows:

  • Accelerate the curing reaction: Adding 0.1%~0.5% (mass fraction) bismuth isooctanoate to polyurethane coatings can significantly shorten the curing time from the original 24 hours to less than 6 hours . This not only increases production efficiency, but also improves the mechanical properties and weather resistance of the coating.
  • Improve product performance: Bismuth isooctanoate can also improve the mechanical properties of polyurethane materials, such as tensile strength, shear strength and peel strength. Experimental results show that the shear strength of polyurethane adhesives containing 0.2% bismuth isooctanoate on stainless steel and glass substrates increased by 20% and 30% respectively.
2. Epoxy resin (EP) curing

Epoxy resin is a high-performance thermosetting resin that is widely used in electronic packaging, composite materials, anti-corrosion coatings and other fields. During the curing process of epoxy resin, bismuth isooctanoate serves as a catalyst, which can significantly accelerate the cross-linking reaction between epoxy groups and amine curing agents, improving the curing speed and product performance. Specific application examples are as follows:

  • Shorten the curing time: Adding 0.1%~0.3% (mass fraction) of bismuth isooctanoate to epoxy resin electronic packaging materials can significantly shorten the curing time from the original 12 hours to within 4 hours. This not only increases production efficiency, but also improves the electrical and mechanical properties of the packaging materials.
  • Improve heat resistance: Bismuth isooctanoate can also improve the heat resistance of epoxy resin, allowing it to maintain good performance in high temperature environments. Experimental results show that the mechanical and electrical properties of epoxy resin containing 0.2% bismuth isooctanoate did not significantly decrease after continuous use for 1,000 hours at 200°C.

Application of bismuth isooctanoate in organic synthesis

1. Dehydration reaction of alcohol

In organic synthesis, the dehydration reaction of alcohol is an important step and is often used to prepare alkenes and ether compounds. As a catalyst, bismuth isooctanoate can significantly improve the dehydration reaction rate and selectivity of alcohol. Specific application examples are as follows:

  • Increase the reaction rate: In the reaction of dehydrating ethanol to prepare ethylene, adding 0.5% (mass fraction) bismuth isooctanoate can significantly increase the reaction rate and allow the reaction to proceed at a lower temperature. Reduce the occurrence of side reactions.
  • Improve selectivity: Bismuth isooctanoate can also improve the selectivity of alcohol dehydration reaction and reduce the formation of by-products. Experimental results show that in a reaction system containing bismuth isooctanoate, the selectivity of ethanol dehydration to ethylene reaches more than 95%.
2. Esterification reaction

Esterification reaction is a common reaction type in organic synthesis and is often used to prepare various ester compounds. Bismuth isooctanoate serves as a catalyst and can significantly increase the rate and yield of the esterification reaction. Specific application examples are as follows:

  • Increase the reaction rate: In the esterification reaction of acetic acid and ethanol, adding 0.3% (mass fraction) bismuth isooctanoate can significantly increase the reaction rate and make the reaction complete in a shorter time. Finish.
  • Improving yield: Bismuth isooctanoate can also increase the yield of esterification reaction and reduce the formation of by-products. Experimental results show that in the reaction system containing bismuth isooctanoate, the yield of ethyl acetate reaches more than 90%.

Application of bismuth isooctanoate in fine chemicals

1. Synthesis of pharmaceutical intermediates

In the synthesis of pharmaceutical intermediates, bismuth isooctanoate serves as a catalyst and can significantly increase the rate and selectivity of the reaction. Specific application examples are as follows:

  • Increase the reaction rate: In the synthesis reaction of certain drug intermediates, adding 0.1%~0.5% (mass fraction) bismuth isooctanoate can significantly increase the reaction rate and make the reaction faster. Completed in a short time.
  • Improve selectivity: Bismuth isooctanoate can also improve the selectivity of the reaction, reduce the formation of by-products, and improve the purity of the target product. Experimental results show that in the reaction system containing bismuth isooctanoate, the purity of the target product reaches more than 98%.
2. Flavor synthesis

In spicesIn the synthesis, bismuth isooctanoate is used as a catalyst, which can significantly improve the rate and selectivity of the reaction. Specific application examples are as follows:

  • Improving the reaction rate: In the synthesis reaction of certain fragrance compounds, adding 0.1%~0.5% (mass fraction) of bismuth isooctanoate can significantly increase the reaction rate and make the reaction shorter. completed within the time limit.
  • Improve selectivity: Bismuth isooctanoate can also improve the selectivity of the reaction, reduce the formation of by-products, and improve the purity of the target product. Experimental results show that in the reaction system containing bismuth isooctanoate, the purity of the target spice reaches more than 95%.

Applications of bismuth isooctanoate in the field of environmental protection

1. Waste gas treatment

In exhaust gas treatment, bismuth isooctanoate serves as a catalyst and can significantly improve the degradation efficiency of organic pollutants in exhaust gas. Specific application examples are as follows:

  • Improve degradation efficiency: When treating waste gas containing VOCs (volatile organic compounds), adding 0.1%~0.5% (mass fraction) of bismuth isooctanoate can significantly improve the degradation efficiency of VOCs. , reduce pollutant emissions.
  • Reducing energy consumption: Bismuth isooctanoate can also reduce the energy consumption of waste gas treatment, allowing the reaction to proceed at a lower temperature, reducing energy consumption. Experimental results show that in the reaction system containing bismuth isooctanoate, the degradation efficiency of VOCs reaches more than 90%.
2. Wastewater treatment

In wastewater treatment, bismuth isooctanoate serves as a catalyst and can significantly improve the degradation efficiency of organic pollutants in wastewater. Specific application examples are as follows:

  • Improve degradation efficiency: When treating wastewater containing organic pollutants, adding 0.1%~0.5% (mass fraction) of bismuth isooctanoate can significantly improve the degradation efficiency of organic pollutants and reduce Discharge of pollutants.
  • Reducing energy consumption: Bismuth isooctanoate can also reduce the energy consumption of wastewater treatment, allowing the reaction to proceed at a lower temperature, reducing energy consumption. Experimental results show that in the reaction system containing bismuth isooctanoate, the degradation efficiency of organic pollutants reaches more than 90%.

Conclusion

In summary, bismuth isooctanoate, as an efficient metal catalyst, has shown broad application prospects in the chemical industry. It can not only significantly increase reaction rate and selectivity in the fields of polymer synthesis, organic synthesis, fine chemicals and environmental protection, but also improve product performance and environmental performance. In the future, with the deepening of research and technological advancement, the application of bismuth isooctanoate in the chemical industry will be more extensive, providing stronger support for the sustainable development of various industries.

Extended reading:
DABCO MP608/Delayed equilibrium catalyst

TEDA-L33B/DABCO POLYCAT/Gel catalyst

Addocat 106/TEDA-L33B/DABCO POLYCAT

NT CAT ZR-50

NT CAT TMR-2

NT CAT PC-77

dimethomorph

3-morpholinopropylamine

Toyocat NP catalyst Tosoh

Toyocat ETS Foaming catalyst Tosoh